Skimmer looks like a promising tool for managing all your social media streams.
Skimmer℠ is an Adobe® AIR™ desktop application designed to streamline, beautify, and enhance the experience of participating in your most frequently used social networking activities. It improves upon your day-to-day interaction with multiple social networks, removing distractions and providing a rich experience that is particularly suited to multimedia content.
For more information The 2.0 Life has a great overview of the tool called Keep Your Social Media Life Organized with Skimmer.
Enjoy!
